Nonmeat Protein Sources on Atherogenic Lipoprotein Measures in the Context of Low Compared with High Saturated Fat Intake: A Randomized Controlled Trial”, The American Journal of Clinical Nutrition 110, no. 1 (2019); Heli E. K. Virtanen et al., “Dietary Proteins and Protein Sources and Risk of Death: The Kuopio Ischaemic Heart Disease Risk Factor Study”, American Journal of Clinical Nutrition 109, no. 5 (2019).

в том числе сероводород: Jose C. Clemente, Julia Manasson, and Jose U. Scher, “The Role of the Gut Microbiome in Systemic Inflammatory Disease”, British Medical Journal 360 (2018); Song and Chan, “Environmental Factors, Gut Microbiota”; E. Magee, “A Nutritional Component to Inflammatory Bowel Disease: The Contribution of Meat to Fecal Sulfide Excretion”, Nutrition 15, no. 3 (March 1999); S. L. Jowett et al., “Influence of Dietary Factors on the Clinical Course of Ulcerative Colitis: A Prospective Cohort Study”, Gut 53, no. 10 (Oct. 2004).

раз за разом обнаруживают доказательства: Dong and Gupta, “Influence of Early Life”. A sugar in red meat: Maria Hedlund et al., “Evidence for a Human-Specific Mechanism for Diet and Antibody-Mediated Inflammation in Carcinoma Progression”, Proceedings of the National Academy of Sciences of the USA 105, no. 48 (Dec. 2, 2008).

Или гемовое железо: Lu Qi et al., “Heme Iron from Diet as a Risk Factor for Coronary Heart Disease in Women with Type 2 Diabetes”, Diabetes Care 30, no. 1 (2007).

и обнаружили их огромное количество в продуктах животного происхождения: Clett Erridge, “The Capacity of Foodstuffs to Induce Innate Immune Activation of Human Monocytes in Vitro Is Dependent on Food Content of Stimulants of Toll-Like Receptors 2 and 4”, British Journal of Nutrition 105, no. 1 (2011).

так много эндотоксинов, что их хватит, чтобы воспалить весь организм: Robert A. Vogel, Mary C. Corretti, and Gary D. Plotnick, “Effect of a Single High-Fat Meal on Endothelial Function in Healthy Subjects”, American Journal of Cardiology 79, no. 3 (Feb. 1, 1997).

где начал свою медицинскую практику: Stephen O’Keefe, email to author, May 2021.

который сделал похожие наблюдения: Brian Kellock, Fiber Man: The Life Story of Dr. Denis Burkit (Tring: Lion Publishing, 1985).

набрал двадцать афроамериканцев: O’Keefe et al., “Fat, Fibre and Cancer Risk”.

в том числе сравнение детей из Буркина-Фасо с детьми из Италии: Carlotta De Filippo et al., “Impact of Diet in Shaping Gut Microbiota Revealed by a Comparative Study in Children from Europe and Rural Africa”, Proceedings of the National Academy of Sciences of the USA 107, no. 33 (2010); H. L. Simpson and B. J. Campbell, “Review Article: Dietary FibreMicrobiota Interactions”, Alimentary Pharmacology and Therapeutics 42 (2015).

благотворение влияние на врожденную и адаптивную ветви иммунной системы: Melanie Schirmer et al., “Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity”, Cell 167, no. 4 (2016); Lisa Rizzetto et al., “Connecting the Immune System, Systemic Chronic Inflammation and the Gut Microbiome: The Role of Sex”, Journal of Autoimmunity 92 (Aug. 2018).

снижают способность жировых клеток усваивать жирные кислоты.: Rizzetto et al., “Connecting the Immune System”. 187 induce Tregs: Herbert Tilg and Alexander R. Moschen, “Food, Immunity, and the Microbiome”, Gastroenterology 148, no. 6 (May 2015); James L. Richards et al., “Dietary Metabolites and the Gut Microbiota: An Alternative Approach to Control Inflammatory and Autoimmune Diseases”, Clinical & Translational Immunology 5, no. 5 (May 2016).

Они помогают разводить спокойные макрофаги: См., например: Shuai Wang et al., “Functions of Macrophages in the Maintenance of Intestinal Homeostasis”, Journal of Immunology Research 2019 (March 2019); Na et al., “Macrophages in Intestinal Inflammation and Resolution”; Song and Chan, “Environmental Factors, Gut Microbiota”; Hideo Ohira, Wao Tsutsui, and Yoshio Fujioka, “Are Short Chain Fatty Acids in Gut Microbiota Defensive Players for Inflammation and Atherosclerosis?”, Journal of Atherosclerosis and Thrombosis 24, no. 7 (2017).

Они проникают через плаценту: Yu Anne Yap and Eliana Mariño, “An Insight into the Intestinal Web of Mucosal Immunity, Microbiota, and Diet in Inflammation”, Frontiers in Immunology 9 (2018).

негативное влияние на иммунные клетки и воспаление в кишечнике: Huawei Zeng et al., “Secondary Bile Acids and Short Chain Fatty Acids in the Colon: A Focus on Colonic Microbiome, Cell Proliferation, Inflammation, and Cancer”, International Journal of Molecular Sciences 20, no. 5 (2019).

коррелирует с размером атеросклеротических бляшек: J. E. Park et al., “Differential Effect of Short-Term Popular Diets on TMAO and Other Cardio-Metabolic Risk Markers”, Nutrition, Metabolism and Cardiovascular Diseases 29, no. 5 (May 1, 2019).

перерабатывали главным образом растительную пищу: Joanna E. Lambert, “Primate Nutritional Ecology: Feeding Biology and Diet at Ecological and Evolutionary Scales”, in Primates in Perspective, ed. Christina Campbell et al. (Oxford: Oxford University Press, 2010); Joanna E. Lambert, “Primate Digestion: Interactions among Anatomy, Physiology, and Feeding Ecology”, Evolutionary Anthropology: Issues, News, and Reviews 7, no. 1 (Jan. 1, 1998).

однако питались главным образом листьями: Peter S. Ungar, Evolution of the Human Diet: The Known, the Unknown, and the Unknowable, Human Evolution Series (Oxford: Oxford University Press, 2007); Lisa Ringhofer, Fishing, Foraging and Farming in the Bolivian Amazon: On a Local Society in Transition (Dordrecht: Springer, 2010).

также питались в основном растительной пищей: Ringhofer, Fishing, Foraging and Farming; H. J. Challa, M. Bandlamudi, and K. R. Uppaluri, “Paleolithic Diet”, in Statpearls (2021).

на окаменелых зубных камнях людей: Jessica Hendy et al., “Proteomic Evidence of Dietary Sources in Ancient Dental Calculus”, Proceedings of the Royal Society B: Biological Sciences 285, no. 1883 (July 25, 2018).

в меньшей степени способствует воспалению: Fatemeh Arya et al., “Differences in Postprandial Inflammatory Responses to a ‘Modern’ V. Traditional Meat Meal: A Preliminary Study”, British Journal of Nutrition 104, no. 5 (Sept. 2010).

Особую опасность представляют диеты: Shivam Joshi, Robert J. Ostfeld, and Michelle McMacken, “The Ketogenic Diet for Obesity and Diabetes – Enthusiasm Outpaces Evidence”, JAMA Internal Medicine 179, no. 9 (2019); Steven R. Smith, “A Look at the Low-Carbohydrate Diet”, New England Journal of Medicine 361 (Dec. 3, 2009); Ilana M. Bank et al., “Sudden Cardiac Death in Association with the Ketogenic Diet”, Pediatric Neurology 39, no. 6 (Dec. 1, 2008); Beth Zupec-Kania and Mary L. Zupanc, “Long-Term Management of the Ketogenic Diet: Seizure Monitoring,